Statins Reach More Patients With Pharmacist’s Orders
PHILADELPHIA — One way of looping remote pharmacists into the primary care clinician workflow successfully boosted statin initiation in the cluster-randomized SUPER LIPID trial. Researchers devised an intervention of asynchronous automated orders, a centralized approach using pharmacists to discuss and prescribe statins without a doctor’s visit. This led to most orders cosigned (73.7%) and a […]
Golden Hour Bundle of Interventions Boosts Outcomes for High-Risk Preterm Infants
WASHINGTON — A multidisciplinary quality improvement (QI) team successfully and safely adhered to a golden hour bundle of interventions for high-risk preterm infants, a researcher said here. Adherence to the bundle also led to reduced rates of severe hypothermia and reduced time to antibiotic administration, as well as a boost to early initiation of IV […]
Lorundrostat Stands a Chance Against Obesity-Related Hypertension
Among selected people with uncontrolled hypertension, blood pressure (BP) could be successfully reduced with a highly selective aldosterone synthase inhibitor, a phase II dose-finding trial found. In hypertensive patients with suppressed renin — theoretically the group most likely to benefit from reining in aldosterone production — reductions of automated office systolic BP reached up to […]
‘Exciting’ siRNA Therapy for Hypertension Passes First Hurdle
Patients with hypertension successfully dialed down their angiotensinogen levels and had lasting reductions in blood pressure (BP) following one injection of an investigational small interfering RNA (siRNA) therapy, according to a phase I study. In this first-in-human, placebo-controlled study, patients who received zilebesiran showed dose-dependent decreases in serum angiotensinogen levels and 24-hour ambulatory BP after […]
Most Patients Successfully Self-Manage Medication Abortion, Study Shows
In several countries, nearly all participants successfully completed a self-managed medication abortion without procedural intervention, a prospective observational study showed. In Argentina, Nigeria, and Southeast Asia, nine out of every ten individuals completed a self-managed medication abortion, which compares with data from randomized clinical trials. Among those who took misoprostol only, 95.7% had success, reported […]
Organosulfur content of vegetables quantified: Selective and sensitive measurement of reactive polysulfides in 22 different vegetables
Osaka Metropolitan University scientists successfully quantified the total reactive polysulfide content of 22 different types of vegetables, including onions and garlic. They also revealed that reactive polysulfides are not only found in the leek genus (Allium), such as onions and garlic but also in the cruciferous family of vegetables (Brassicaceae), such as broccoli and cabbage. […]
Pattern of gene activity for ADHD
Researchers at the National Institutes of Health (NIH) have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD). The study, led by scientists at the National Human Genome Research Institute (NHGRI), part of the NIH, found that individuals diagnosed with ADHD had differences in genes that code […]
‘Traffic calming’ boosts breeding on coral reefs
Coral reef fish breed more successfully if motorboat noise is reduced, new research shows. Scientists introduced “traffic calming” on three reefs for an entire breeding season — cutting the number of boats within 100m, and reducing the speed of those within that distance. They then tracked the breeding of fish called spiny chromis — and […]
New treatment to combat obesity and heart disease
An interdisciplinary research team at The University of Texas at San Antonio has successfully developed an innovative inhibitor that shows promise in fighting obesity and potentially preventing heart disease. Francis Yoshimoto, an assistant professor in the UTSA College of Sciences’ Department of Chemistry, is leading a team that developed an anti-obesity drug that blocks the […]
Biodiversity loss in plants worldwide
When alien plants integrate into an existing ecosystem and successfully spread there, in rare cases this can contribute to the increased uniqueness of the regional flora. However, much more often this process — known as “naturalization” — leads to a homogenization of regional floras and thus to a net loss of global floristic uniqueness. Especially […]