Escalated ADT Falls Short in Men With High-Risk Features After Prostatectomy
SAN FRANCISCO — Add-on hormone therapy plus an antiandrogen to salvage radiation and androgen deprivation therapy (ADT) did not boost survival outcomes in high-risk prostate cancer. In the FORMULA-509 trial, the addition of 6 months of abiraterone acetate (Zytiga) and apalutamide (Erleada) to salvage radiation (RT) and 6 months of ADT with a GnRH agonist […]
Pediatric Sarcoma Patients Face Late Amputation Risk Decades Later
BALTIMORE — Pediatric patients who underwent limb salvage surgery (LSS) for lower extremity sarcomas had a substantial risk of undergoing late amputation, a researcher reported. In a retrospective analysis of data from the Childhood Cancer Survivor Study (CCSS), the cumulative incidence of late amputation at 20 years after LSS was almost one out of every […]