Golden Hour Bundle of Interventions Boosts Outcomes for High-Risk Preterm Infants
WASHINGTON — A multidisciplinary quality improvement (QI) team successfully and safely adhered to a golden hour bundle of interventions for high-risk preterm infants, a researcher said here. Adherence to the bundle also led to reduced rates of severe hypothermia and reduced time to antibiotic administration, as well as a boost to early initiation of IV […]
Trial: Functional Scoring a Better Guide to Neonatal Opioid Withdrawal Tx
A newer function-based approach to treating neonatal opioid withdrawal syndrome safely readied babies to go home sooner, the ACT NOW randomized trial showed. With the Eat, Sleep, Console care approach, time from birth to medical readiness for hospital discharge by American Academy of Pediatrics-endorsed standards was nearly a week sooner than when treating guided by […]
Making Low-Dose tPA Work for Japanese DOAC Users With Ischemic Stroke
Despite concerns about the potential bleeding risk, IV thrombolysis could be safely given to ischemic stroke patients within a day of direct oral anticoagulant (DOAC) therapy, according to observational data from Japan. Between DOAC users and peers not taking oral anticoagulants within 48 hours of stroke onset, rates of symptomatic intracranial hemorrhage, accompanied by a […]
Potential strategy for fighting obesity: Lab safely replicates weight-loss benefits of plant linked to harmful side effects
UT Southwestern scientists may have identified a method of safely mimicking the weight-loss benefits of a plant compound that — despite its harmful side effects — hold critical answers to developing therapies for obesity. Celastrol, derived from the root extracts of a white-flowered plant in China, has drawn increased attention in recent years after studies […]
Monoclonal antibody may prevent malaria
One dose of a new monoclonal antibody discovered and developed at the National Institutes of Health safely prevented malaria for up to nine months in people who were exposed to the malaria parasite. The small, carefully monitored clinical trial is the first to demonstrate that a monoclonal antibody can prevent malaria in people. The trial […]