Removing largest serving sizes of wine decreases alcohol consumption, study finds
Across 21 licensed premises in England, removing the largest individual serving size of wine from the menu reduced the volume of wine sold, according to a new study publishing January 18 in the open access journal PLOS Medicine by Theresa Marteau of the University of Cambridge, UK, and colleagues. Alcohol consumption is the fifth largest […]
Do Away With ‘Lockout’ Period in iPLEDGE, FDA Advisors Urge
An FDA advisory committee on Wednesday voted 17-4 (with one abstention) to recommend removing a “lockout period” from a risk evaluation and mitigation strategy (REMS) for isotretinoin prescribing that requires patients to wait an extra 19 days — and take an additional pregnancy test — if they miss a 7-day window for picking up their […]
Removing Small Asymptomatic Kidney Stones Significantly Reduces Recurrence
Removing small, asymptomatic kidney stones during endoscopic removal of ureteral or contralateral stones significantly prolonged the time to relapse as compared with leaving the asymptomatic stones behind, a randomized trial showed. The time to relapse averaged about 4.5 years with removal of asymptomatic stones versus about 2.5 years without (P<0.001). The difference represented an 82% […]
One-Word Change in Prostate Cancer Guideline Has Some Urologists in Arms
The National Comprehensive Cancer Network (NCCN) is under fire for removing active surveillance’s (AS) “preferred” status in its low-risk prostate cancer guidelines. AS has been listed as preferred since 2019, and the change puts it on par with radical prostatectomy and radiation therapy in this patient population. Edward “Ted” Schaeffer, MD, PhD, chairman of the […]
Could Nixing Race-Adjustments for eGFR Harm Black Cancer Patients?
Removing race from estimated glomerular filtration rate (eGFR) equations would result in fewer Black patients being eligible for certain anticancer drugs, researchers have demonstrated. Their analysis showed that for Black patients, removing race from the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation reduced median eGFR from 103 mL/min to 89 mL/min. In addition, removing the race […]