Reproductive History Linked to Later Stroke Risk
A history of infertility, recurrent miscarriage, or stillbirth may be a risk factor for stroke later in life, according to an analysis of eight prospective cohort studies. Among over 600,000 women, infertility was associated with an increased risk of non-fatal stroke (HR 1.14, 95% CI 1.08-1.20), while a history of at least three miscarriages was […]
Immuno-Oncology Combo Active in Recurrent EGFR/ALK Positive NSCLC
Patients with recurrent EGFR/ALK-positive non-small cell lung cancer (NSCLC) obtained durable remissions with the combination of pembrolizumab (Keytruda) and chemotherapy, a small prospective study showed. The immuno-oncology (IO) combination led to a median progression-free survival (PFS) of 8.3 months in EGFR-mutant NSCLC and overall survival (OS) of 22.2 months. The combination had limited activity in […]