Topical Gel Soothes Skin Rash for CRC Patients on EGFR Inhibitors

The use of an investigational topical BRAF-inhibiting gel appeared to be effective in treating acneiform rash in patients with advanced colorectal cancer who were treated with an epidermal growth factor receptor (EGFR)-targeted drug, a randomized phase II trial showed. The 39 patients randomly assigned to receive a high-dose 0.1% formulation of LUT014 gel were twice […]

Unprecedented Response Rates in Non-Responsive, Non-Muscle Invasive Bladder Cancer

LAS VEGAS — Patients with high-risk, treatment-unresponsive non-muscle invasive bladder cancer (NMIBC) had an unprecedented response rate and disease-free survival (DFS) with an investigational intravesical treatment system, data from an ongoing trial showed. Complete responses (CR) occurred in 82.4% of 85 patients treated with TAR-200, a system that delivers gemcitabine directly into the bladder. The […]