Alzheimer’s Disease Detected in Blood a Decade Before Clinical Symptoms
Blood concentrations of glial fibrillary acidic protein (GFAP), a marker of astrogliosis, were higher about 10 years before symptom onset in an inherited form of Alzheimer’s disease. Three plasma biomarkers — phosphorylated tau (p-tau181), neurofilament light chain (NfL), and GFAP — were higher in mutation carriers than non-carriers in a Swedish cohort of autosomal dominant […]