Rhythmic eating pattern preserves fruit fly muscle function under obese conditions
Obese fruit flies are the experimental subjects in a Nature Communications study of the causes of muscle function decline due to obesity. In humans, skeletal muscle plays a crucial role in metabolism, and muscle dysfunction due to human obesity can lead to insulin resistance and reduced energy levels. Interestingly, studies in various animal models have […]
Using new technique, researchers make surprising discoveries about how flies’ brains respond to tastes
Taste matters to fruit flies, just as it does to humans: like people, the flies tend to seek out and consume sweet-tasting foods and reject foods that taste bitter. However, little is known about how sweet and bitter tastes are represented by the brain circuits that link sensation to behavior. In a new study published […]
Calorie restriction trial reveals key factors in extending human health
Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans remains unclear. Now a new study led by Yale researchers confirms the health benefits of moderate calorie restrictions in humans — and […]
More filling? Tastes great? How flies, and maybe people, choose their food
Flies have discriminating taste. Like a gourmet perusing a menu, they spend much of their time seeking sweet nutritious calories and avoiding bitter, potentially toxic food. But what happens in their brains when they make these food choices? Yale researchers discovered an interesting way to find out. They tricked them. In a study that could […]