Lurie Children’s partners with ISBE on online platform to support student mental health

The Center for Childhood Resilience at Ann and Robert H. Lurie Children’s Hospital of Chicago said Thursday they have rolled out a new statewide online platform to provide schools with tools to strengthen student mental health.

ADC-Pertuzumab Promising as New Standard in HER2-Positive Metastatic Breast Cancer

CHICAGO — First-line trastuzumab deruxtecan (T-DXd) combined with pertuzumab (Perjeta) improved progression-free survival (PFS) in HER2-positive locally advanced or metastatic breast cancer, according to the DESTINY-Breast09 trial. In the phase III study after a median of follow-up of 29 months, patients randomized to T-DXd plus pertuzumab had a median PFS by blinded independent central review […]

Alternative Endpoints in Phase III Trials Don’t Always Mean Boosts to OS, QOL

CHICAGO — Late-phase trials that showed superiority for an experimental intervention on a surrogate endpoint did not necessarily lead to improvements in overall survival (OS) or quality of life (QOL), according to a meta-epidemiologic analysis. Alexander Dean Sherry, MD of the MD Anderson Cancer Center in Houston, and colleagues evaluated 791 randomized controlled trials (RCTs) […]

A Chicago Hospital Bows to Federal Pressure on Trans Care for Teens

He’s 17 and lives in the Chicago suburbs. He loves theater and recently helped direct a play at his high school. He takes competitive AP courses and is working on his Eagle Scout project. And he’s been on a journey for 4 years. Once a week, the transgender teen injects testosterone into his body. He’s […]