Topical Gel Soothes Skin Rash for CRC Patients on EGFR Inhibitors

The use of an investigational topical BRAF-inhibiting gel appeared to be effective in treating acneiform rash in patients with advanced colorectal cancer who were treated with an epidermal growth factor receptor (EGFR)-targeted drug, a randomized phase II trial showed. The 39 patients randomly assigned to receive a high-dose 0.1% formulation of LUT014 gel were twice […]

Do GLP-1 Drugs Pose a Risk to Lung Transplant Recipients?

People taking GLP-1 receptor agonists appeared to be at elevated risk of rejection episodes after lung transplantation, a small, single-center cohort study suggested. In a retrospective review of 301 consecutive lung transplants, the 34 lung recipients taking a GLP-1 drug for diabetes or obesity early in their post-transplant course had 15.19-fold (95% CI 2.08-23.55, P<0.05) […]