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Another Win for a JAK Inhibitor in Alopecia Areata

NEW ORLEANS — Patients with severe alopecia areata had dramatic hair regrowth at 6 months with an investigational Janus kinase (JAK) inhibitor, according to a study reported here. Almost 40% of patients had at least 80% scalp coverage with the higher of two doses of the JAK 1/2 inhibitor deuruxolitinib (CTP-543), including 35% who had […]

5-ARIs Not Linked to Risk of Dementia Over the Long Term

Men taking 5α-reductase inhibitors (5-ARIs), commonly used for androgenic alopecia and benign prostatic hyperplasia (BPH), should be aware of possible adverse psychological effects, researchers warned. In a register-based cohort study of over 2.2 million Swedish men, an increased risk for depression was seen in those taking finasteride (Proscar, Propecia; HR 1.61, 95% CI 1.48-1.75) or […]

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